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Category 1 vs. Category 2. The FDA's peptide update, explained. Category 2 peptides are on the FDA's “difficult to compound” list, which effectively blocks licensed pharmacies from producing them. Category 1 means

The inability to absorb vitamin B-12 from the intestinal tract can lead to various types of anemia, the most prominent of which is a type of megaloblastic anemia called pernicious anemia

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[DOI] [PubMed] [Google Scholar] 84.Gallo C., Renzi P., Loizzo S., Loizzo A., Piacente S., Festa M., Caputo M., Tecce M.F., Capasso A